This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn’s disease: retrospective long-term follow-up of the LIR!C trial. Lancet Gastroenterol Hepatol 2020; 5: 900-907.

Published: 9th June 2021

Authors: Stevens TW, Haasnoot GR, Buskens CJ, de Groof EJ, Eshuis EJ, Gardenbroek TJ et al.

Conclusion

Some 134 of the original 143 patients were available for study after a median of 63.5 months. Thirty-one (48 percent) of the patients in the infliximab group subsequently had a bowel resection. Some 29 patients (42 per cent) in the surgery group had no further medical treatment, and a further 48% had prophylactic infliximab only.

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