General - British Journal of Surgery

Scientific Surgery

Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury. A double-blind, placebo-controlled, randomized clinical trial. JAMA Surg 2020; 156: 11-20.

Authors: Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ et al.

Scientific Surgery

Prophylactic topical tranexamic acid versus placebo in surgical patients. A systematic review and meta-analysis. Ann Surg 2021; 273: 676-683.

Authors: Teoh WY, Tan TG, Ng KT, Ong KX, Chan XL, Hung T et al.

Scientific Surgery

Preventing recurrence in clean and contaminated hernias using biologic versus synthetic mesh in ventral hernia repair. The PRICE randomized clinical trial. Ann Surg 2021; 273: 648-655.

Authors: Harris H, Primus F, Young C, Carter JT, Lin M, Mukhtar R et al.

Scientific Surgery

Patient-reported outcomes of robotic vs laparoscopic ventral hernia repair with intraperitoneal mesh. The PROVE-IT randomized clinical trial. JAMA Surg 2021; 156: 22-29.

Authors: Petro CC, Zolin S, Krpata D, Alkhatib H, Tu C, Rosen MJ et al.

Scientific Surgery

Simple wound Irrigation in the postoperative treatment for surgically drained spontaneous soft tissue abscesses: a prospective, randomized controlled trial. World J Surg 2020; 44: 4041-4051.

Authors: Oehme F, Ruhle A, Bornert K, Hempel S, Link B-C, Babst R et al.

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Snapshot quiz (April 2021 [1])

A 42-year-old woman presented with a 3-month history of dyspepsia, weight loss, and vague upper abdominal pain. On examination a palpable umbilical nodule was found. What is this clinical sign called?

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Scientific Surgery

Effect of prophylactic embolization on patients with blunt trauma at high risk of splenectomy. A Randomized Clinical Trial. JAMA Surg 2020; 155: 1102-1111.

Authors: Arvieux C, Frandon J, Tidadini F, Monnin-Bares V, Foote A, Dubuisson V et al.

Scientific Surgery

Negative pressure wound therapy vs conventional wound treatment in subcutaneous abdominal wound healing impairment. The SAWHI randomized clinical trial. JAMA Surg 2020; 155: 469-478.

Authors: Seidel D, Diedrich S, Herrle F, Thielemann H, Marusch F, Schirren R et al.

Scientific Surgery

Synthetic versus biological mesh in laparoscopic and open ventral hernia repair (LAPSIS). Results of a multinational, randomized, controlled, and double-blind trial. Ann Surg 2021; 273: 57-65.

Authors: Miserez M, Lefering R, Famiglietti F, Mathes T, Seidel D, Sauerland S et al.

Scientific Surgery

Robotic inguinal vs transabdominal laparoscopic inguinal hernia repair. The RIVAL randomized clinical trial. JAMA Surg 2020; 155: 380-387.

Authors: Prabhu A, Carbonell A, Hope W, Warren J, Higgins R, Jacob B et al.

Scientific Surgery

A single preoperative dose of tranexamic acid reduces perioperative blood loss. A meta-analysis. Ann Surg 2021; 273: 75-81.

Authors: Heyns M, Knight P, Steve AK, Yeung JK

Scientific Surgery

Primary open versus closed implantation strategy for totally implantable venous access ports. The Multicentre Randomized Controlled PORTAS-3 Trial (DRKS 00004900). Ann Surg 2020; 272: 950-960.

Authors: Hüttner F, Bruckner T, Hackbusch M, Weitz J, Bork U, Kotschenreuther P et al.

Scientific Surgery

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial Lancet 2020; 396: 1653-1662.

Authors: Jochmans I, Brat A, Davies L, Hofker HS, van de Leemkolk FEM, Leuvenink HGD et al.

Scientific Surgery

Effect of e-cigarettes plus counseling vs counseling alone on smoking cessation. A randomized clinical trial. JAMA 2020; 324: 1844-1854.

Authors: Eisenberg MJ, Hébert-Losier A, Windle SB, Greenspoon T, Brandys T, Fülöp T et al.

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Snapshot quiz (January 2021)

A 45-year-old woman with a history of an old burn injury to the chest and abdominal wall presented with a progressive ulcerated lesion on her right flank. What is the diagnosis?

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Scientific Surgery

Preoperative patient-specific flow predictions to improve arteriovenous fistula maturation (Shunt Simulation Study): a randomised controlled trial. Eur J Vasc Endovasc Surg 2020; 60: 98-106.

Authors: Zonnebeld N, Tordoir JHM, van Loon MM, de Smet AA, Huisman LC, Cuypers PW et al.

Scientific Surgery

Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial. Lancet 2020; 396: 1353-1361.

Authors: Richards T, Baikady RR, Clevenger B, Butcher A, Abeysiri S, Chau M et al.

Scientific Surgery

Telemedicine to follow patients in a general surgery department. A randomized controlled trial. Am J Surg 2020; 219: 882-887.

Authors: Cremades M, Ferret G, Pares D, Navines J, Espin F, Pardo F et al.

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