Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Pancreaticojejunostomy: Does the technique matter? A randomized trial. J Surg Oncol 2018; 117: 389-396.

Authors: Singh AN, Pal S, Mangla V, Kilambi R, George J, Dash NR et al.

Scientific Surgery

Efficacy of a dual-ring wound protector for prevention of surgical site infections after pancreaticoduodenectomy in patients with intrabiliary stents: a randomized clinical trial. Ann Surg 2018; 268: 35-40.

Authors: Bressan A, Aubin J-M, Martel G, Dixon E, Bathe O, Sutherland F et al.

Scientific Surgery

Does Braun anastomosis have an impact on the incidence of delayed gastric emptying and the extent of intragastric bile reflux following pancreatoduodenectomy? A randomized controlled study. Dig Surg 2017; 34: 462-468.

Authors: Fujieda H, Yokoyama Y, Hirata A, Usui H, Sakatoku Y, Fukaya M et al.

Scientific Surgery

Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet 2017; 390: 1027–1037.

Authors: Diener MK, Hüttner FJ, Keiser M, Knebel P, Dörr-Harim C, Distler M et al.

Scientific Surgery

Early enteral versus total parenteral nutrition in patients undergoing pancreaticoduodenectomy: a randomized multicenter controlled trial (Nutri-DPC). Ann Surg 2016; 264: 731-737.

Authors: Perinel J, Mariette C, Dousset B, Sielezneff I, Gainant A, Mabrut J-Y et al.

Scientific Surgery

Perioperative hydrocortisone reduces major complications after pancreaticoduodenectomy: a randomized controlled trial. Ann Surg 2016; 264: 696-702.

Authors: Laaninen M, Sand J, Nordback I, Vasama K, Laukkarinen J

Scientific Surgery

Duct-to-mucosa vs invagination for pancreaticojejunostomy after pancreaticoduodenectomy: a prospective, randomized controlled trial from a single surgeon. J Am Coll Surg 2016; 222: 10-18.

Authors: Bai X, Zhang Q, Gao S, Lou J, Li G, Zhang Y et al.

Scientific Surgery

Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after PANcreatoduodenectomy (RECOPANC, DRKS 00000767): perioperative and long-term results of a multicentre randomized controlled trial. Ann Surg 2016; 263: 440-449.

Authors: Keck T, Wellner UF, Bahra M, Klein F, Sick O, Niedergethmann M et al.

Scientific Surgery

Papillary-like main pancreatic duct invaginated pancreaticojejunostomy versus duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy: A prospective randomized trial. Surgery 2015; 158: 1211–1218.

Authors: Xu J, Zhang B, Shi S, Qin Y, Ji S, Xu W et al. et al.

Scientific Surgery

Stump closure reinforcement with absorbable fibrin collagen sealant sponge (TachoSil) does not prevent pancreatic fistula after distal pancreatectomy: the FIABLE multicenter controlled randomized study. Am J Surg 2015; 210: 739-748.

Authors: Sa Cunha A, Carrere N, Meunier B, Fabre J-M, Sauvanet A, Pessaux P et al. et al.

Scientific Surgery

The HYSLAR Trial: a prospective randomized controlled trial of the use of a restrictive fluid regimen with 3% hypertonic saline versus lactated Ringersâ–’ in patients undergoing pancreaticoduodenectomy. Ann Surg 2014; 260: 445-455.

Authors: Lavu H, Sell NM, Carter TI, Winter J, Maguire DP, Gratch DM et al. et al.

Scientific Surgery

Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study. World J Surg 2014; 38: 465-475.

Authors: Tamandi D, Sahora K, Prucker J, Schmid R, Holst JJ, Miholic J et al. et al.

Scientific Surgery

Pressurized pulse irrigation with saline reduces surgical site infections following major hepatobiliary and pancreatic surgery: a randomized controlled trial. World J Surg 2014; 38: 447-455.

Authors: Nikfarjam M, Weiberg L, Fink MA, Muralidharan V, Starkey G, Jones R et al. et al.

Scientific Surgery

Antecolic versus retrocolic route of gastroenteric anastomosis after pancreatoduodenectomy: a randomized, controlled trial. Ann Surg 2014; 259: 45-51.

Authors: Eshuis WJ, van Eijck CHJ, Gerhards MF, Coene PP, de Hingh IHJT, Karsten TM et al. et al.

Scientific Surgery

A prospective, randomised trial of Roux-en-Y reconstruction with isolated pancreatic drainage versus conventional loop reconstruction pancreaticoduoenectomy. Surgery 2013; 153: 743–752.

Authors: Ke S, Ding X-M, Gao J, Zhao A-M, Deng G, Ma R-L et al. et al.

Scientific Surgery

Effect of Billroth II or Roux-en-Y reconstruction for the gastrojejunostomy on delayed gastric emptying after pancreaticoduodenectomy: a randomized controlled study. Ann Surg 2013; 257: 938-942.

Authors: Shimoda M, Kubota K, Katoh M, Kita J

Scientific Surgery

Efficacy of an absorbable fibrin sealant patch (TachoSil) after distal pancreatectomy: a multicenter, randomized, controlled trial. Ann Surg 2012; 256: 853–860.

Authors: Montorsi M, Zerbi A, Bassi C, Capussotti L, Coppola R, Sacchi M et al. et al.

Scientific Surgery

A meta-analysis of outcomes following use of somatostatin and its analogues for the management of enterocutaneous fistulas. Ann Surg 2012; 256: 946–954.

Authors: Rahbour GB, Siddiqui MR, Ullah MR, Gabe SM, Warusavitarne JB, Vaizey CJ et al.

Scientific Surgery

Ultrasonic dissection versus conventional dissection techniques in pancreatic surgery: a randomized multicentre study. Ann Surg 2012; 256: 675–680.

Authors: Uzunoglu FG, Stehr A, Fink JA, Vettorazzi E, Koenig A, Gawad KA et al. et al.

Scientific Surgery

The methods of reconstruction of pancreatic digestive continuity after pancreaticoduodenectomy: a meta-analysis of randomized controlled trials. World J Surg 2011; 35: 2290–2297.

Authors: Yang SH, Dou KF, Sharma N, Song WJ

Scientific Surgery

Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy. Ann Surg 2011; 253: 495–501.

Authors: Kawai M, Tani M, Hirono S, Miyazawa M, Shimizu A, Uchiyama K et al. et al.

Scientific Surgery

External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trial. Ann Surg 2011; 253: 879–885.

Authors: Pessaux P, Sauvanet A, Mariette C, Paye F, Muscari F, Cunha AS et al. et al.

Scientific Surgery

Relationship between intraoperative fluid administration and perioperative outcome after pancreaticoduodenectomy: results of a prospective randomized trial of acute normovolemic hemodilution compared with standard intraoperative management. Ann Surg 2010; 252: 952–958.

Authors: Fischer M, Matsuo K, Gonen M, Grant F, DeMatteo RP, D’Angelica MI et al. et al.

Scientific Surgery

Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med 2010; 362: 129-137.

Authors: Van der Gaag NA, Rauws EAJ, van Eijck CHJ, Bruno MJ, van der Harst E, Kubben FJGM et al. et al.

Scientific Surgery

Randomized, placebo-controlled, double-blind study of the efficacy of lanreotide 30 mg PR in the treatment of pancreatic and enterocutaneous fistulae. Ann Surg 2009; 250: 872-877.

Authors: Gayral F, Campion J-P, Regimbeau J-M, Blumberg J, Masionobe P, Topart P et al. et al.

Scientific Surgery

Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy J Surg Oncol 2008; 98: 309-313

Authors: Uemura K, Murakami Y, Hayashidani Y, Sudo T, Hashimoto Y, Ohge H et al et al.

Scientific Surgery

Prophylactic octreotide and delayed gastric emptying after pancreaticoduodenectomy: results of a prospective randomized, double-blinded placebo-controlled trial. Eur J Surg Oncol 2008; 34: 868-875.

Authors: Kollmar O, Moussavian MR, Richter S, de Roi P, Maurer CA, Schilling MK. et al.

Scientific Surgery

External drainage of pancreatic duct with a stent to reduce leakage rate after pancreaticoduodenectomy: a prospective randomized trial. Ann Surg 2007; 246: 425-433.

Authors: Poon RT, Fan ST, Lo CM, Ng KK, Yeun WK, Yeung C et al.

Scientific Surgery

Use of octreotide for the prevention fistula after elective pancreatic surgery: a systematic review and meta-analysis. Can J Surg 2007; 50: 459¿466.

Authors: Alghamdi AA, Jawas AM, Hart RS.

Scientific Surgery

Effect of enteral nutrition and synbiotics on bacterial infection rates after pylorus-preserving pancreatoduodenectomy: a randomised, double-blind trial. Ann Surg 2007; 246: 36-41.

Authors: Rayes N, Seehofer D, Theruvath T, Mogl M, Langrehr J, Nussler NC et al.

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