Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 700-708.

Authors: Wu L, Shang R, Sharma P, Zhou W, Liu J, Yao L et al.

Scientific Surgery

Short-term outcomes of robotic gastrectomy vs laparoscopic gastrectomy for patients with gastric cancer. A randomized clinical trial. JAMA Surg 2021; 156: 954-963.

Authors: Ojima T, Nakamura M, Hayata K, Kitadani J, Katsuda M, Takeuchi A et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss and quality of life at 7 Years in patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA Surg 2021; 156: 137-146.

Authors: Gronroos S, Helmio M, Juuti A, Tiusanen R, Hurme S, Loyttyniemi E et al.

Scientific Surgery

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 120-127.

Authors: Kono K, Misawa K, Yabusaki H, Kinoshita T, Lau PC, Kim YW et al.

Scientific Surgery

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.

Scientific Surgery

Effect of gastric bypass vs best medical treatment on early-stage chronic kidney disease in patients with type 2 diabetes and obesity. A randomized clinical trial. JAMA Surg 2020; 155: e200420.

Authors: Cohen RV, Pereira TV, Aboud CM, Petry TBZ, Correa JLL, Schiavon CA et al.

Scientific Surgery

Efficacy and safety of ursodeoxycholic acid for the prevention of gallstone formation after gastrectomy in patients with gastric cancer. The PEGASUS-D randomized clinical trial. JAMA Surg 2020; 155: 703-711.

Authors: Lee SH, Jang DK, Yoo M-W, Hwang S-H, Ryu S-Y, Kwon OK et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.

Scientific Surgery

Banded versus nonbanded sleeve gastrectomy. A randomized controlled trial with 3 years of follow-up. Ann Surg 2020; 272: 690-695.

Authors: Fink J, Hetzenecker A, Seifert G, Runkel M, Laessle C, Fichtner-Feigl S et al.

Scientific Surgery

Efficacy and safety of the duodeno-jejunal bypass liner in patients with metabolic syndrome. A multicenter randomized controlled trial (ENDOMETAB). Ann Surg 2020; 272: 696-702.

Authors: Caiazzo R, Branche J, Raverdy V, Czernichow S, Carette C, Robert M et al.

Scientific Surgery

Safety and efficacy of indocyanine green tracer-guided lymph node dissection during laparoscopic radical gastrectomy in patients with gastric cancer. A randomized clinical trial. JAMA Surg 2020; 155: 300-311.

Authors: Chen Q-Y, Xie J-W, Zhong Q, Wang J-B, Lin J-X, Lu J et al.

Scientific Surgery

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut 2020; 69: 859–867.

Authors: El-Salhy M, Hatlebakk JG, Gilja OH, Kristoffersen AB, Hausken T

Scientific Surgery

Luglio G, Rispo A, Imperatore N, Giglio MC, Amendola A, Tropeano FP et al. Surgical prevention of anastomotic recurrence by excluding mesentery in Crohn’s Disease: the SuPREMe-CD Study – A Randomized Clinical Trial. Ann Surg 2020; 272: 210-217.

Authors: Luglio G , Rispo A, Imperatore N, Giglio MC, Amendola A, Tropeano FP et al.

Scientific Surgery

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020; 395: 1927-1936.

Authors: The HALT-IT Trial Collaborators

Scientific Surgery

Effect of laparoscopic distal gastrectomy vs open distal gastrectomy on long-term survival among patients with stage I gastric cancer. The KLASS-01 Randomized Clinical Trial. JAMA Oncol 2019; 5: 506-513.

Authors: Kim H-H, Han S-U, Kim M-C, Kim W, Le H-J, Ryu SW et al.

Scientific Surgery

Prophylactic angiographic embolisation after endoscopic control of bleeding to high-risk peptic ulcers: a randomised controlled trial. Gut 2019; 68: 796-803

Authors: Lau JYW, Pittayanon R, Wong K-T, Pinjaroen N, Chiu PWY, Rerknimitr R et al.

Scientific Surgery

Pouch versus no pouch following total gastrectomy: meta-analysis of randomized and non-randomized studies. Ann Surg 2019; 269: 1041-1053.

Authors: Syn N, Wee I, Shabbir A, Kim G, So JB-Y

Scientific Surgery

Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer. The CLASS-01 randomized clinical trial. JAMA 2019; 321: 1983-1992.

Authors: Yu J, Huang C, Sun Y, Su X, Cao H, Hu J et al.

Scientific Surgery

Efficacy of transversus abdominis plane (TAP) block in pain management after laparoscopic sleeve gastrectomy (LSG): A double-blind randomized controlled trial. Am J Surg 2019; 217: 126-132.

Authors: Saber AA, Lee YC, Arjun C, Namik O, Armand A, Al-Ayoubi S et al.

Scientific Surgery

Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet 2019; 393: 1299-1309.

Authors: Maud R, Espalieu P, Pelascini E, Caiazzo R, Sterkers A, Khamphommala L et al.

Scientific Surgery

Effect of perioperative oral nutritional supplementation in malnourished patients who undergo gastrectomy: a prospective randomized trial. Surgery 2018; 164: 1263-1270.

Authors: Kong S-H, Lee H-J, Na J-R, Kim WG, Han D-S, Park S-H et al.

Scientific Surgery

Effectiveness of fibrin sealant application on the development of staple line complications after sleeve gastrectomy: a prospective randomized trial. Ann Surg 2018; 268: 762-768.

Authors: Rebibo L, Dhahri A, Chati R, Cosse C, Huet E, Regimbeau J-M et al.

Scientific Surgery

Comparison of 3D laparoscopic gastrectomy with a 2D procedure for gastric cancer: a phase 3 randomized controlled trial. Surgery 2018; 163: 300-304.

Authors: Zheng C-H, Lu J, Zheng H-L, Li P, Xie J-W, Wang J-B et al.

Scientific Surgery

Laparoscopy-assisted versus open D2 distal gastrectomy for advanced gastric cancer: results from a randomized phase II multicenter clinical trial (COACT 1001). Ann Surg 2018; 267: 638-645.

Authors: Park YK, Yoon HM, Kim Y-W, Park JY, Ryu KW, Lee Y-J et al.

Scientific Surgery

Helicobacter pylori therapy for the prevention of metachronous gastric cancer. N Engl J Med 2018; 378: 1085-1095.

Authors: Choi IJ, Kook M-C, Kim Y-I, Cho S-J, Lee JY, Kim CG et al.

Scientific Surgery

Adjuvant chemoradiotherapy with epirubicin, cisplatin, and fluorouracil compared with adjuvant chemoradiotherapy with fluorouracil and leucovorin after curative resection of gastric cancer: results from CALGB 80101 (Alliance). J Clin Oncol 2017; 35: 3671-3677.

Authors: Fuchs CS, Niedzwiecki D, Mamon HJ, Tepper JE, Xing Y, Swanson RS et al.

Scientific Surgery

Roux-en-Y or Billroth II reconstruction after radical distal gastrectomy for gastric cancer: a multicenter randomized controlled trial. Ann Surg 2018; 267: 236-242.

Authors: So JB-Y, Rao J, Wong AS-Y, Chan Y-H, Pang NQ, Tay AYL et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity. The SM-BOSS randomized clinical trial. JAMA 2018; 319: 255-265.

Authors: Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D , Borbély Y et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA 2018; 319: 241-254.

Authors: Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P et al.

Scientific Surgery

Effect of intravenous ferric carboxymaltose on hemoglobin response among patients with acute isovolemic anemia following gastrectomy. The FAIRY Randomized Clinical Trial. JAMA. 2017; 317: 2097-2104.

Authors: Kim Y-W, Bae J-M, Park Y-K, Yang H-K, Yu W, Yook JH et al.

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