Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Comparison of the efficacy of chlorhexidine gluconate versus povidone iodine as preoperative skin preparation for the prevention of surgical site infections in clean-contaminated upper abdominal surgeries. Surg Today 2015; 45: 1378-1384.

Authors: Srinivas A, Kaman L, Raj P, Gautam V, Dahiya D, Singh G et al. et al.

Scientific Surgery

Safety and hemostatic effectiveness of the fibrin pad for severe soft-tissue bleeding during abdominal, retroperitoneal, pelvic, and thoracic (non-cardiac) surgery: a randomized, controlled, superiority trial. World J Surg 2015; 39: 2663-2669.

Authors: Koea J, Baldwin P, Shen J, Patel B, Batiller J, Arnaud A et al. et al.

Scientific Surgery

Aerosolized intraperitoneal local anesthetic for laparoscopic surgery: a randomized, double-blinded, placebo-controlled trial. World J Surg 2015; 39: 1681-1689.

Authors: McDermott AM, Chang KH, Mieske K, McAnena PF, Kinirons B, Abeidi A et al. et al.

Scientific Surgery

Erythromycin for gastric emptying in patients undergoing general anesthesia for emergency surgery. A randomized clinical trial. JAMA Surg 2015; 150: 730-737.

Authors: Czarnetzki C, Elia N, Frossard J-L, Giostra E, Spahr L, Waeber J-L et al. et al.

Scientific Surgery

Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial. Lancet 2015; 386: 1254–1260.

Authors: Deerenberg EB, Harlaar JJ, Steyerberg EW, Lont E, van Doorn HC et al.

Scientific Surgery

Clonidine in patients undergoing noncardiac surgery. N Engl J Med 2014; 370: 1504-1513.

Authors: Devereaux P, Sessler DI, Leslie K, Kurz A, Mrkobrada M, Alonso-Coello P et al. et al.

Scientific Surgery

High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. Lancet 2014; 384: 495-503.

Authors: The PROVE network Investigators

Scientific Surgery

Perioperative aspirin and clonidine and risk of acute kidney injury. JAMA 2014; 312: 2254-2264.

Authors: Garg AX, Kurz A, Sessler DI, Cuerden M, Robinson A, Mrkobrada M et al. et al.

Scientific Surgery

Aspirin in patients undergoing noncardiac surgery. N Engl J Med 2014; 370: 1494-1503.

Authors: Devereaux PJ, Mrkobrada M, Sessler DI, Leslie K, Alonso-Coello P, Kurz A et al. et al.

Scientific Surgery

Multicenter double-blinded randomized controlled trial of standard abdominal wound edge protection with surgical dressings versus coverage with sterile circular polyethylene drape for prevention of surgical site infections. Ann Surg 2014; 260: 730-739.

Authors: Mihaljevic A, Schirren R, Ozer M, Otti S, Grun S, Michalski CW et al. et al.

Scientific Surgery

Effect of perioperative cardiac output guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery. A randomized clinical trial and systematic review. JAMA 2014; 311: 2181-2190.

Authors: Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G et al. et al.

Scientific Surgery

Effectiveness of triclosan-coated PDS plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial. Lancet 2014; 384: 142-152.

Authors: Diener MK, Knebel P, Keiser M, Schuler P, Schiergens TS, Atanassov V et al. et al.

Scientific Surgery

Hydroxyethyl starch reduces coagulation competence and increases blood loss during major surgery: results from a randomized controlled trial. Ann Surg 2014; 259: 249-254.

Authors: Rasmussen KC, Johansson PI, Hojskov M, Kridina I, Kistorp T, Thind P et al. et al.

Scientific Surgery

Benefits and harms of adhesion barriers for abdominal surgery: a systematic review and meta-analysis. Lancet 2014; 383: 48-59.

Authors: Ten Broek RPG, Stommel MWJ, Strik C, van Laarhoven CJHM, Keus F, van Goor H et al.

Scientific Surgery

Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials. Ann Surg 2014; 259: 1056-1067.

Authors: Popping D, Elia N, Van Aken HK, Marret E, Schug SA, Kranke P et al. et al.

Scientific Surgery

Single-port versus conventional multiport laparoscopic surgery: a meta-analysis of randomized controlled studies and non-randomized studies. J Lap Adv Surg Tech 2013; 23: 815-831.

Authors: Qui J, Yuan H, Chen S, He Z, Han P, Wu H et al.

Scientific Surgery

Impact of preoperative local water-filtered infrared A irradiation on postoperative wound healing: a randomized patient- and observer-blinded controlled clinical trial. Ann Surg 2013; 258: 887–894.

Authors: Kunzli BM, Liebl F, Nuhn P, Schuster T, Friess H, Hartel M et al.

Scientific Surgery

Early versus traditional postoperative oral feeding in patients undergoing elective colorectal surgery: a meta-analysis of randomized clinical trials. Dig Surg 2013; 30: 225–232.

Authors: Zhuang C.-L, Ye X.-Z, Zhang C.-J, Dong Q.-T, Chen B.-C, Yu Z et al.

Scientific Surgery

Early oral feeding versus traditional postoperative care after abdominal emergency surgery: a randomized controlled trial. World J Surg 2013; 37: 2293-2299.

Authors: Klappenbach RF, Yazi FJ, Quintas FA, Horna ME, Rodriguez JA, Oria A et al.

Scientific Surgery

Use of safety scalpels and other safety practices to reduce sharps injury in the operating room: what is the evidence? Can J Surg 2013; 56: 263-269.

Authors: DeGirolamo KM, Courtemanche DJ, Hill WD, Kennedy A, Skarsgard ED

Scientific Surgery

Up and down or side to side? A systematic review and meta-analysis examining the impact of incision on outcomes after abdominal surgery. Am J Surg 2013; 206: 400-409.

Authors: Bickenbach KA, Karanicolas PJ, Ammori JB, Jayaraman S, Winter JM, Fields RC et al. et al.

Scientific Surgery

Is there an evidence-based argument for embracing an antimicrobial (triclosan)-coated suture technology to reduce the risk for surgical-site infections? A meta-analysis. Surgery 2013; 154: 89-100.

Authors: Edmiston CE Jr, Daoud FC, Leaper D

Scientific Surgery

Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial). BMJ 2013; 347: f4305.

Authors: Pinkney TD, Calvert M, Bartlett DC, Gheorge A, Redman V, Dowswell G et al. et al.

Scientific Surgery

Prospective, multicentre, randomized controlled trial of bladder filling prior to trial of void on the timing of discharge. Aust NZ J Surg 2013; 83: 239-242.

Authors: Du J, Marshall D, Leyland J, Shaw L, Broome KE, Mason DFC et al.

Scientific Surgery

Intraoperative local insufflation of warmed humidified CO2 increases open wound and core temperatures: a randomised clinical trial. World J Surg 2012; 36: 2567–2575.

Authors: Frey JMK, Janson M, Svanfeldt M, Svenarud PK, van der Linden JA

Scientific Surgery

Triclosan-impregnated sutures to decrease surgical site infections: systematic review and meta-analysis of randomised trials. Ann Surg 2012; 255: 854–859.

Authors: Chang WK, Srinivasa S, Morton R, Hill AG

Scientific Surgery

A meta-analysis of the effect of combinations of immune modulating nutrients on outcome in patients undergoing major open gastrointestinal surgery. Ann Surg 2012; 255: 1060-1068.

Authors: Marimuthu K, Varadhan K, Ljungqvist O, Lobo D

Scientific Surgery

Preoperative glucocorticoid use in major abdominal surgery: systematic review and meta-analysis of randomized trials. Ann Surg 2011; 254: 183-191.

Authors: Srinivasa S, Kahokehr AA, Yu T-C, Hill AG.

Scientific Surgery

Adhesion prevention during laparotomy: long-term follow-up of a randomised clinical trial. Ann Surg 2011; 253: 1118–1121.

Authors: van der Wal JBC, Iordens GIT, Vrijland WW, van Veen RN, Lange J, Jeekel J. et al.

Scientific Surgery

Perioperative epidural analgesia for major abdominal surgery for cancer and recurrence-free survival: randomised trial. BMJ 2011; 342: d1491.

Authors: Myles PS, Peyton P, Silbert B, Hunt J, Rigg JRA, Sessler D et al for the ANZCA Trials Group Investigators. et al.

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