Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial. Lancet 2018; 391: 51–58.

Authors: Van Brunschot S, van Grinsven J, van Santvoort HC, Bakker OJ, Besselink MG, Boermeester MA et al.

Scientific Surgery

Local treatment of unresectable colorectal liver metastases: results of a randomized phase II trial. J Natl Cancer Inst 2017; 109. doi: 10.1093/jnci/djx015.

Authors: Ruers T, Van Coevorden F, Punt CJA, Pierie J-PEN, Borel-Rinkes I, Ledermann JA et al.

Scientific Surgery

A Prospective randomized multicenter trial of distal pancreatectomy with and without routine intraperitoneal drainage. Ann Surg 2017; 266: 421-431.

Authors: Van Buren G , Bloomston M, Schmidt CR, Behrman SW, Zyromski NJ, Ball C et al.

Scientific Surgery

Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet 2017; 390: 1027–1037.

Authors: Diener MK, Hüttner FJ, Keiser M, Knebel P, Dörr-Harim C, Distler M et al.

Scientific Surgery

Interest of using ropivacaine for outpatient laparoscopic cholecystectomy: prospective randomized trial. World J Surg 2017; 41: 687–692.

Authors: Abet E, Orion F, Denimal F, Brau-Weber A-G, De Kerviler B, Jean M-H et al.

Scientific Surgery

Effect of polyglycolic acid mesh for prevention of pancreatic fistula following distal pancreatectomy. A randomized clinical trial. JAMA Surg 2017; 152: 150-155.

Authors: Jang J-Y, Shin YC, Han YM, Park JS, Han H-S, Hwang HK et al.

Scientific Surgery

Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet 2017; 389: 1011–24.

Authors: Neoptolemos JP, Palmer DH, Ghaneh P, Psarelli EE, Valle JW, Halloran CM et al.

Scientific Surgery

Antireflux versus conventional plastic stent in malignant biliary obstruction: a prospective randomized study. J Laparoendosc Adv Surg Tech 2017; 27: 53-57.

Authors: Vihervaara H, Grönroos JM, Hurme S, Gullichsen R, Salminen P

Scientific Surgery

The cost of postoperative pancreatic fistula versus the cost of pasireotide: results from a prospective randomized trial. Ann Surg 2017; 265: 11-16.

Authors: Ma LW , Dominguez-Rosado I, Gennarelli RL, Bach PB, Gonen M, D’Angelica M et al.

Scientific Surgery

Continuous wound infiltration versus epidural analgesia after hepato-pancreatoibiliary surgery (POP-UP): a randomised controlled open-label, non-inferiority trial. Lancet Gastroenterol Hepatol 2016; 1: 105-113.

Authors: Mungroop TH, Veelo DP, Busch OR, van Gulik TM, Karsten TM, de Castro SM et al.

Scientific Surgery

Effect of N-acetylcysteine on liver recovery after resection: A randomized clinical trial. J Surg Oncol 2016; 114: 446–450.

Authors: Grendar J, Ouellet JF, McKay A, Sutherland FR, Bathe OF, Ball CG et al.

Scientific Surgery

Early enteral versus total parenteral nutrition in patients undergoing pancreaticoduodenectomy: a randomized multicenter controlled trial (Nutri-DPC). Ann Surg 2016; 264: 731-737.

Authors: Perinel J, Mariette C, Dousset B, Sielezneff I, Gainant A, Mabrut J-Y et al.

Scientific Surgery

Teres ligament patch reduces relevant morbidity after distal pancreatectomy (the DISCOVER randomized controlled trial). Ann Surg 2016; 264: 723-730.

Authors: Hassenpflug M, Hinz U, Strobel O, Volpert J, Knebel P, Diener M et al.

Scientific Surgery

Perioperative hydrocortisone reduces major complications after pancreaticoduodenectomy: a randomized controlled trial. Ann Surg 2016; 264: 696-702.

Authors: Laaninen M, Sand J, Nordback I, Vasama K, Laukkarinen J

Scientific Surgery

Early versus delayed cholecystectomy for acute cholecystitis, are the 72 hours still the rule?: a randomized trial. Ann Surg 2016; 264: 717-722.

Authors: Roulin D, Saadi A, Di Mare L, Demartines N, Halkic N

Scientific Surgery

Prospective randomized controlled trial of liberal vs. restricted perioperative fluid management in patients undergoing pancreatectomy. Ann Surg 2016; 264: 591-598.

Authors: Grant F, Brennan MF, Allen PJ,, DeMatteo RP, Kingham TP, D’Angelica M et al.

Scientific Surgery

No need for routine drainage after pancreatic head resection: the dual-center, randomized controlled PANDRA Trial. Ann Surg 2016; 264: 528-537.

Authors: Witzigmann H, Diener MK, Kienkötter S, Rossion I, Bruckner T, Bärbel W et al.

Scientific Surgery

Evaluation of the efficacy of daikenchuto (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery 2016; 159: 1333–1341.

Authors: Okada K-I, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M et al.

Scientific Surgery

Fibrin sealant patch (TachoSil) vs oxidized regenerated cellulose patch (Surgicel Original) for the secondary treatment of local bleeding in patients undergoing hepatic resection: a randomized controlled trial. J Am Coll Surg 2012; 222: 261-268.

Authors: Genyk Y, Kato T, Pomposelli JJ, Wright Jr JK, Sher LS, Tetens V et al.

Scientific Surgery

Fibrin sealant with polyglycolic acid felt vs fibrinogen-based collagen fleece at the liver cut surface for prevention of postoperative bile leakage and hemorrhage: a prospective, randomized, controlled study. J Am Coll Surg 2016; 222: 59-64.

Authors: Kobayashi S, Takeda Y, Nakahira S, Tsujie M, Shimizu J, Miyamoto A et al.

Scientific Surgery

Randomized controlled trial of pancreaticojejunostomy versus stapler closure of the pancreatic stump during distal pancreatectomy to reduce pancreatic fistula. Ann Surg 2016; 264: 180-187.

Authors: Kawai M, Hirono S, Okada K, Sho M, Nakajima Y, Eguchi H et al.

Scientific Surgery

Duct-to-mucosa vs invagination for pancreaticojejunostomy after pancreaticoduodenectomy: a prospective, randomized controlled trial from a single surgeon. J Am Coll Surg 2016; 222: 10-18.

Authors: Bai X, Zhang Q, Gao S, Lou J, Li G, Zhang Y et al.

Scientific Surgery

Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after PANcreatoduodenectomy (RECOPANC, DRKS 00000767): perioperative and long-term results of a multicentre randomized controlled trial. Ann Surg 2016; 263: 440-449.

Authors: Keck T, Wellner UF, Bahra M, Klein F, Sick O, Niedergethmann M et al.

Scientific Surgery

Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial. Lancet 2016; 387: 2293–2301.

Authors: Luo H, Zhao L, Leung J, Zhang R, Liu Z, Wang X et al.

Scientific Surgery

Single-incision laparoscopic cholecystectomy versus traditional laparoscopic cholecystectomy performed by a single surgeon: findings of a randomized trial. Surg Today 2016; 46: 313-318.

Authors: Partelli S, Barugola G, Sartori A, Crippa S, Falconi M, Ruffo G et al.

Scientific Surgery

Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01). Lancet 2016; 388: 248–25716.

Authors: Uesaka K, Boku N, Kukutomi A, Okamura Y, Knoishi M, Matsumoto I et al.

Scientific Surgery

Pilot randomized controlled trial of laparoscopic cholecystectomy vs active nonoperative therapy for the treatment of biliary dyskinesia. J Am Coll Surg 2016; 222: 1156–1163.

Authors: Richmond BK, Grodman C, Walker J, Dean S, Tiley EH, Hamrick RE et al.

Scientific Surgery

Management and outcome of borderline common bile duct with stones: a prospective randomized study. J Lap Adv Surg Tech A 2016; 26: 161-167.

Authors: El Nakeeb A, El Geidie A, El Hanafy E, Atef E, Askar W, Sultan AM et al.

Scientific Surgery

Effect of covered metallic stents compared with plastic stents on benign biliary stricture resolution: a randomized clinical trial. JAMA. 2016; 315: 1250-1257.

Authors: Coté GA, Slivka A, Tarnasky P, Mullady DK, Elmunzer J, Elta G et al.

Scientific Surgery

Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study). Cancer 2016; 122: 574-581.

Authors: Leone F, Marino D, Cereda S, Filippi R, Belli C, Spadi R et al.

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