Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss and quality of life at 7 Years in patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA Surg 2021; 156: 137-146.

Authors: Gronroos S, Helmio M, Juuti A, Tiusanen R, Hurme S, Loyttyniemi E et al.

Scientific Surgery

Effect of gastric bypass vs best medical treatment on early-stage chronic kidney disease in patients with type 2 diabetes and obesity. A randomized clinical trial. JAMA Surg 2020; 155: e200420.

Authors: Cohen RV, Pereira TV, Aboud CM, Petry TBZ, Correa JLL, Schiavon CA et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.

Scientific Surgery

Banded versus nonbanded sleeve gastrectomy. A randomized controlled trial with 3 years of follow-up. Ann Surg 2020; 272: 690-695.

Authors: Fink J, Hetzenecker A, Seifert G, Runkel M, Laessle C, Fichtner-Feigl S et al.

Scientific Surgery

Efficacy and safety of the duodeno-jejunal bypass liner in patients with metabolic syndrome. A multicenter randomized controlled trial (ENDOMETAB). Ann Surg 2020; 272: 696-702.

Authors: Caiazzo R, Branche J, Raverdy V, Czernichow S, Carette C, Robert M et al.

Scientific Surgery

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut 2020; 69: 859–867.

Authors: El-Salhy M, Hatlebakk JG, Gilja OH, Kristoffersen AB, Hausken T

Scientific Surgery

Luglio G, Rispo A, Imperatore N, Giglio MC, Amendola A, Tropeano FP et al. Surgical prevention of anastomotic recurrence by excluding mesentery in Crohn’s Disease: the SuPREMe-CD Study – A Randomized Clinical Trial. Ann Surg 2020; 272: 210-217.

Authors: Luglio G , Rispo A, Imperatore N, Giglio MC, Amendola A, Tropeano FP et al.

Scientific Surgery

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020; 395: 1927-1936.

Authors: The HALT-IT Trial Collaborators

Scientific Surgery

Prophylactic angiographic embolisation after endoscopic control of bleeding to high-risk peptic ulcers: a randomised controlled trial. Gut 2019; 68: 796-803

Authors: Lau JYW, Pittayanon R, Wong K-T, Pinjaroen N, Chiu PWY, Rerknimitr R et al.

Scientific Surgery

Efficacy of transversus abdominis plane (TAP) block in pain management after laparoscopic sleeve gastrectomy (LSG): A double-blind randomized controlled trial. Am J Surg 2019; 217: 126-132.

Authors: Saber AA, Lee YC, Arjun C, Namik O, Armand A, Al-Ayoubi S et al.

Scientific Surgery

Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet 2019; 393: 1299-1309.

Authors: Maud R, Espalieu P, Pelascini E, Caiazzo R, Sterkers A, Khamphommala L et al.

Scientific Surgery

Effectiveness of fibrin sealant application on the development of staple line complications after sleeve gastrectomy: a prospective randomized trial. Ann Surg 2018; 268: 762-768.

Authors: Rebibo L, Dhahri A, Chati R, Cosse C, Huet E, Regimbeau J-M et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity. The SM-BOSS randomized clinical trial. JAMA 2018; 319: 255-265.

Authors: Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D , Borbély Y et al.

Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA 2018; 319: 241-254.

Authors: Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus Roux-Y-gastric bypass for morbid obesity: 3-year outcomes of the prospective randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS). Ann Surg 2017; 265: 466-473.

Authors: Peterli R, Wölnerhanssen BK, Vetter D, Nett P, Gass M, Borbély Y et al.

Scientific Surgery

Standard vs distal Roux-en-Y gastric bypass in patients with body mass index 50 to 60. A double-blind, randomized clinical trial. JAMA Surg 2016; 151: 1146-1155.

Authors: Risstad H, Svanevik M, Kristinsson JA, Hjelmesæth J, Aasheim T, Hofsø D et al.

Scientific Surgery

Impact of surgical technique on long-term complication rate after laparoscopic adjustable gastric banding (LAGB): results of a single-blinded randomized controlled trial (ANOSEAN Study). Ann Surg 2016; 264: 738-744.

Authors: Le Coq B, Frering V, Ghunaim M, Campan P, Dabrowski A, Mulliez E et al.

Scientific Surgery

Closure of mesenteric defects in laparoscopic gastric bypass: a multicentre, randomised, parallel, open-label trial. Lancet 2016; 387: 1397–1404.

Authors: Stenberg E, Szabo E, Ågren G, Ottosson J, Marsk R, Lönroth H et al.

Scientific Surgery

A prospective randomized controlled trial of laparoscopic repair versus open repair for perforated peptic ulcers. Surgery 2016; 159: 451–458.

Authors: Ge B, Wu M, Chen Q, Chen Q, Lin R, Liu L et al.

Scientific Surgery

Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment. A randomized clinical trial. JAMA Surg 2015; 150: 931-940.

Authors: Courcoulas AP, Belle SH, Neiberg RH, Pierson SK, Eagleton JK, Kalarchian MA et al. et al.

Scientific Surgery

Bariatric–metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial. Lancet 2015; 386: 964–973.

Authors: Mingrone G, Panunzi S, De Gaetano A, Guidone C, Iaconelli A, Nanni G et al. et al.

Scientific Surgery

A prospective randomized multicentre trial of Surgisis Gold, a biologic prosthetic, as a sublay reinforcement of the fascial closure after open bariatric surgery. Surgery 2014; 156: 902-909.

Authors: Sarr MG, Hutcher NE, Snyder S, Hodde J, Carmody B

Scientific Surgery

Double oral esomeprazole after a 3-day intravenous esomeprazole infusion reduces recurrent peptic ulcer bleeding in high-risk patients: a randomised controlled study. Gut 2014; 63: 1864-1872.

Authors: Cheng HC, Wu CT, Chang WL, Cheng WC, Chen VVY, Sheu BS et al.

Scientific Surgery

The effect of the endoscopic duodenal-jejunal bypass liner on obesity and Type 2 diabetes mellitus, a multicenter randomized controlled trial. Ann Surg 2014; 260: 984-992.

Authors: Koehestanie P, de Jonge C, Berends FJ, Janssen IM, Bouvy ND, Greve JW et al.

Scientific Surgery

Randomized pilot trial of bariatric surgery versus intensive medical weight management on diabetes remission in Type 2 diabetic patients who do NOT meet NIH criteria for surgery and the role of soluble RAGE as a novel biomarker of success. Ann Surg 2014; 260: 617-624.

Authors: Parikh M, Chung M, Sheth S, McMacken M, Zahra T, Saunders JK et al. et al.

Scientific Surgery

Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity. The ReCharge randomized clinical trial. JAMA 2014; 32: 915-922.

Authors: Ikramuddin SI, Blackstone RP, Brancatisano A, Toouli J, Shah SN, Wolfe BW et al. et al.

Scientific Surgery

Feasibility and one year results of a randomized clinical trial. JAMA Surg 2014; 149: 716-726.

Authors: Halperin F, Ding S-A, Simonson DC, Panosian J, Goebel-Fabbri A, Wewalka M et al. et al.

Scientific Surgery

Surgical vs. medical treatments for type II diabetes mellitus. A randomized clinical trial. JAMA Surg 2014; 149: 707-715.

Authors: Courcoulas AP, Goodpaster BH, Eagleton JK, Belle SH, Kalarchian MA, Lang W et al. et al.

Scientific Surgery

Multinational, double-blind, randomised, placebo controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study. Gut 2014; 63: 1061-1068.

Authors: Sugano K, Choi M-G, Lin J-T, Goto S, Okada Y, Kinoshita Y et al. et al.

Scientific Surgery

Enhanced postoperative recovery pathways in emergency surgery: a randomised clinical trial. Am J Surg 2014; 207: 807-814.

Authors: Gonenc M, Dural AC, Celik F, Akarsu C, Kocatas A, Kalayci MU et al. et al.

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