Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea. Gut 2014; 63: 1617-1625.

Authors: Garsed K, Chernova J, Hastings M, Lam C, Marciani L, Singh G et al. et al.

Scientific Surgery

Meta-analysis of randomized trials on single incision laparoscopic versus conventional laparoscopic appendectomy. Am J Surg 2014; 207: 613-622.

Authors: Antoniou SA, Koch OO, Antoniou GA, Lasithiotakis K, Chalkiadakis GE, Pointer R et al. et al.

Scientific Surgery

Systematic review and meta-analysis of randomized controlled trials comparing single incision versus conventional laparoscopic appendectomy. World J Surg 2014; 38: 1937-1946.

Authors: Clerveus M, Morandeira-Rivas A, Moreno-Sanz C, Herrero-Bogajo ML, Picazo-Yeste JS, Tadeo-Ruiz G et al.

Scientific Surgery

Continuous absorbable intradermal sutures yield better cosmetic results than nonabsorbable interrupted sutures in open appendectomy wounds: a prospective, randomized trial. World J Surg 2014; 38: 1044-1050.

Authors: Koskela A, Kotaluoto S, Kaartinen I, Pauniaho SL, Rantanen T, Kuokkanen H et al.

Scientific Surgery

A prospective, randomized controlled trial of single-incision laparoscopic vs. conventional 3-port laparoscopic appendectomy for treatment of acute appendicitis. J Am Coll Surg 2014; 218: 950-959.

Authors: Carter JT, Kaplan JA, Nguyen JA, Lin MYC, Rogers SJ, Harris HW et al.

Scientific Surgery

Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in elderly inpatients (PLACIDE): a randomised double-blind, placebo-controlled multicentre trial. Lancet 2013; 382: 1249-1257.

Authors: Allen SJ, Wareham K, Wang D, Bradley C, Hutchings H, Harris W et al. et al.

Scientific Surgery

Safety and efficacy of knotless anastomosis with a barbed suture for gastrointestinal suture: a prospective and randomized study on obese patients undergoing gastric bypass. J Laparoendosc Adv Surg Tech A 2013; 23: 756–759.

Authors: Milone M, Di Minno MN, Galloro G, Maietta P, Bianco P, Milone F et al. et al.

Scientific Surgery

A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn’s disease. Gut 2013; 62: 1288–1294.

Authors: Sands BE, Katz S, Wolf DC, Feagan BG, Wang T, Gustofson LM et al. et al.

Scientific Surgery

Comparative study between single-incision and three-port laparoscopic appendectomy: a prospective randomised trial. J Lap Adv Surg Tech 2013; 23: 431–436.

Authors: Kye BH, Lee J, Kim W, Kim D, Lee D

Scientific Surgery

Randomized prospective study to compare laparoscopic appendectomy versus umbilical single-incision appendectomy. Ann Surg 2013; 257: 413-418.

Authors: Frutos MD, Abrisqueta J, Lujan J, Abellan I, Parilla P

Scientific Surgery

Warm, humidified carbon dioxide gas insufflation for laparoscopic appendicectomy in children: a double-blinded randomized controlled trial. Ann Surg 2013; 257: 44–53.

Authors: Yu TC, Hamill JK, Liley A, Hill AG

Scientific Surgery

Single-port laparoscopic appendectomy versus conventional laparoscopic appendectomy: a prospective randomised controlled study. Ann Surg 2013; 257: 214–218.

Authors: Lee WS, Choi ST, Lee JN, Kim KK, Park YH, Lee WK et al. et al.

Scientific Surgery

Wound healing after open appendectomies in adult patients: a prospective, randomised trial comparing two methods of wound closure. World J Surg 2012; 36: 2305–2310.

Authors: Kotaluoto S, Pauniaho S-L, Helminen M, Kuokkanen H, Rantanen T

Scientific Surgery

A double-blinded randomized controlled trial of laparoendoscopic single-site access versus conventional 3-port appendectomy. Ann Surg 2012; 256: 909–914.

Authors: Teoh AYB, Chiu PWY, Wong TCL, Poon MCM, Wong SKH, Leong HT et al. et al.

Scientific Surgery

HAnd suture versus STApling for closure of loop ileostomy (HASTA Trial): results of a multicenter randomized trial. Ann Surg 2012; 256: 828–836.

Authors: Loffler T, Rossion I, Bruckner T, Diener MK, Koch M, von Frankenberg M et al. et al.

Scientific Surgery

Irrigation versus suction alone during laparoscopic appendectomy for perforated appendicitis: a prospective randomised trial. Ann Surg 2012; 256: 581-585.

Authors: St Peter SD, Adibe OO, Iqbal CW, Fike FB, Sharp SW, Juang D et al. et al.

Scientific Surgery

One vs. three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial. JAMA 2012; 307: 1265-1272.

Authors: Joensuu H, Eriksson M, Sundby HK, Hartmann JT, Pink D, Schutte J et al. et al.

Scientific Surgery

Low-dose abdominal CT for evaluating suspected appendicitis. N Engl J Med 2012; 366: 1596-1605.

Authors: Kim K, Kim YH, Kim SY, Kim S, Lee YJ, Kim KP et al. et al.

Scientific Surgery

Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials. BMJ 2012; 344: e2156.

Authors: Varadhan KK, Neal KR, Lobo DN

Scientific Surgery

Use of antibiotics alone for treatment of uncomplicated acute appendicitis: a systematic review and meta-analysis. Surgery 2011; 150: 673–683.

Authors: Liu K, Fogg L.

Scientific Surgery

Maneuvers to decrease laparoscopy-induced shoulder and upper abdominal pain. A randomized controlled study. Arch Surg 2011; 146: 1360–1366.

Authors: Tsai H-W, Chen Y-J, Ho C-M, Hseu S-S, Chao K-C, Tsai S-K et al. et al.

Scientific Surgery

Antibiotics versus appendectomy in the management of acute appendicitis: a review of current evidence. Can J Surg 2011; 54: 307–314.

Authors: Fitzmaurice GJ, McWilliams B, Hurreiz H, Epanomeritakis E

Scientific Surgery

Single incision versus standard 3-port laparoscopic appendectomy. A prospective randomized trial. Ann Surg 2011; 254: 586-590.

Authors: St Peter SD, Adibe OO, Juang D, Sharp SW, Garey CL, Laituri CA et al.

Scientific Surgery

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome. Gut 2011; 60: 902–914.

Authors: Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B, O’Keefe SJ. et al.

Scientific Surgery

Early vs. interval appendectomy for children with perforated appendicitis. Arch Surg. 2011; 146: 660–605.

Authors: Blakely ML, Williams R, Dassinger MS, Eubanks JW, Fischer P, Huang EY et al. et al.

Scientific Surgery

Surgery versus conservative antibiotic treatment in acute appendicitis: a systematic review and meta-analysis of randomized controlled trials. Dig Surg 2011; 28: 210–221.

Authors: Ansaloni L, Catena F, Coccolini F, Ercolani G, Gazzotti F, Pasqualini E et al. et al.

Scientific Surgery

Amoxicillin plus clavulanic acid versus appendicetomy for treatment of acute uncomplicated appendicitis: an open-label, non inferiority, randomised controlled trial. Lancet 2011; 377: 1573–1579.

Authors: Vons C, Barry C, Maitre S, Pautrat K, Leconte M, Costaglioli B et al. et al.

Scientific Surgery

Perioperative hyperoxygenation and wound site infection following surgery for acute appendicitis. A randomized, prospective, controlled trial. Arch Surg 2011; 146: 464–470.

Authors: Bickel A, Gurevits M, Varnos R, Ivry S, Eitan A.

Scientific Surgery

Significant reduction of wound infections with daily probing of contaminated wounds. A prospective randomized clinical trial. Arch Surg 2011; 146: 448–452.

Authors: Towfigh S, Clarke T, Yacoub W, Pooli AH, Mason RJ, Katkhouda N et al.

Scientific Surgery

Infliximab, azathioprine or combination therapy for Crohn’s Disease. N Engl J Med 2010; 362: 1383-95.

Authors: Colombel JF, Sandborn WJ, Reinisch W, Mantzaris GJ, Kombluth A, Rachmilewitz D et al. et al.

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