Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Early complications in delayed breast reconstruction: A prospective, randomized study comparing different reconstructive methods in radiated and non-radiated patients. Eur J Surg Oncol 2020; 46: 2208-2217.

Authors: Brorson F, Thorarinsson A, Kolby L, Elander A, Hansson E

Scientific Surgery

Effect of capecitabine maintenance therapy using lower dosage and higher frequency vs observation on disease-free survival among patients with early-stage triple-negative breast cancer who had received standard treatment. The SYSUCC-001 Randomized Clinical Trial. JAMA 2021; 325: 50-58.

Authors: Wang X, Wang S-S, Huang H, Cai L, Peng R-J, Lin Y et al.

Scientific Surgery

Effect of prophylactic embolization on patients with blunt trauma at high risk of splenectomy. A Randomized Clinical Trial. JAMA Surg 2020; 155: 1102-1111.

Authors: Arvieux C, Frandon J, Tidadini F, Monnin-Bares V, Foote A, Dubuisson V et al.

Scientific Surgery

Randomized controlled trial of compression after endovenous thermal ablation of varicose veins (COMETA Trial). Ann Surg 2021; 273: 232-239.

Authors: Bootun R, Belramman A, Bolton-Saghdaoui L, Lane T, Riga C, Davies A et al.

Scientific Surgery

Long-term clinical and cost-effectiveness of early endovenous ablation in venous ulceration. A randomized clinical trial. JAMA Surg 2020; 155: 1113-1121.

Authors: Gohel M, Mora J, Szigeti M, Epstein DM, Heatley F, Bradbury A et al.

Scientific Surgery

Negative pressure wound therapy vs conventional wound treatment in subcutaneous abdominal wound healing impairment. The SAWHI randomized clinical trial. JAMA Surg 2020; 155: 469-478.

Authors: Seidel D, Diedrich S, Herrle F, Thielemann H, Marusch F, Schirren R et al.

Scientific Surgery

Two-stage Turnbull-Cutait pull-through coloanal anastomosis for low rectal cancer. A randomized clinical trial. JAMA Surg 2020; 155: e201625.

Authors: Biondo S, Trenti L, Espin E, Bianco F, Barrios O, Falato A et al.

Scientific Surgery

Simultaneous versus delayed resection for initially resectable synchronous colorectal cancer liver metastases. A prospective, open-label, randomized, controlled trial. Ann Surg 2021; 273: 49-56.

Authors: Boudjema K, Locher C, Sabbagh C, Ortega-Deballon P, Heyd B, Bachellier P et al.

Scientific Surgery

A systematic review and network-meta-analysis of gastro-enteric reconstruction techniques following pancreatoduodenectomy to reduce delayed gastric emptying. World J Surg 2020; 44: 2314-2322.

Authors: Kamarajah SK, Bundred JR, Alessandri G, Robinson SM, Wilson CH, French JJ et al.

Scientific Surgery

Efficacy and safety of ursodeoxycholic acid for the prevention of gallstone formation after gastrectomy in patients with gastric cancer. The PEGASUS-D randomized clinical trial. JAMA Surg 2020; 155: 703-711.

Authors: Lee SH, Jang DK, Yoo M-W, Hwang S-H, Ryu S-Y, Kwon OK et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.

Scientific Surgery

Synthetic versus biological mesh in laparoscopic and open ventral hernia repair (LAPSIS). Results of a multinational, randomized, controlled, and double-blind trial. Ann Surg 2021; 273: 57-65.

Authors: Miserez M, Lefering R, Famiglietti F, Mathes T, Seidel D, Sauerland S et al.

Scientific Surgery

Robotic inguinal vs transabdominal laparoscopic inguinal hernia repair. The RIVAL randomized clinical trial. JAMA Surg 2020; 155: 380-387.

Authors: Prabhu A, Carbonell A, Hope W, Warren J, Higgins R, Jacob B et al.

Scientific Surgery

Mortality with paclitaxel-coated devices in peripheral artery disease. N Engl J Med 2020; 383: 2538-2546.

Authors: Nordanstig J, James, S, Andersson M, Andersson M, Danielsson P, Gillgren P et al.

Scientific Surgery

A single preoperative dose of tranexamic acid reduces perioperative blood loss. A meta-analysis. Ann Surg 2021; 273: 75-81.

Authors: Heyns M, Knight P, Steve AK, Yeung JK

Scientific Surgery

Prospective, randomized study on the use of prosthetic mesh to prevent a parastomal hernia in a permanent colostomy: results of a long-term follow-up. Dis Colon Rectum 2020; 63: 678-684.

Authors: Mäkäräinen-Uhlbäck EJ, Klintrup KHB, Vierimaa MT, Carpelan-Holmström MA, Kössi JAO, Kairaluoma MV et al.

Scientific Surgery

Heated fennel therapy promotes the recovery of gastrointestinal function in patients after complex abdominal surgery: A single-center prospective randomized controlled trial in China. Surgery 2020; 168: 793-799.

Authors: Chen B, He Y, Xiao Y, Guo D, Liu P, He Y et al.

Scientific Surgery

Minimal open hemorrhoidectomy versus transanal hemorrhoidal dearterialization: the effect on symptoms: an open-label randomized controlled trial. Dis Colon Rectum 2020; 63: 655-667.

Authors: Rørvik H, Campos AH, Styr K, Ilum L, McKinstry GK, Brandstrup B et al.

Scientific Surgery

Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials. Lancet Oncol 2020; 21: 1620-1629.

Authors: Andre T, Meyerhardt J, Iveson T, Sobrero A, Yoshino T, Souglakos I et al.

Scientific Surgery

Banded versus nonbanded sleeve gastrectomy. A randomized controlled trial with 3 years of follow-up. Ann Surg 2020; 272: 690-695.

Authors: Fink J, Hetzenecker A, Seifert G, Runkel M, Laessle C, Fichtner-Feigl S et al.

Scientific Surgery

Laser ablation versus mechanochemical ablation in the treatment of primary varicose veins: A randomized clinical trial. J Vasc Venous 2020; 8: 211-215.

Authors: Tawfik AM, Sorour WA, El-Laboudy ME

Scientific Surgery

Heparin-bonded versus standard polytetrafluoroethylene arteriovenous grafts: A Bayesian perspective on a randomized controlled trial for comparative effectiveness. Surgery 2020; 168: 1066-1074.

Authors: Nissen AP, Sandhu HK, Perlick AP, Martin GH, Miller CC, Charlton-Ouw KM et al.

Scientific Surgery

Primary open versus closed implantation strategy for totally implantable venous access ports. The Multicentre Randomized Controlled PORTAS-3 Trial (DRKS 00004900). Ann Surg 2020; 272: 950-960.

Authors: Hüttner F, Bruckner T, Hackbusch M, Weitz J, Bork U, Kotschenreuther P et al.

Scientific Surgery

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial Lancet 2020; 396: 1653-1662.

Authors: Jochmans I, Brat A, Davies L, Hofker HS, van de Leemkolk FEM, Leuvenink HGD et al.

Scientific Surgery

Effect of e-cigarettes plus counseling vs counseling alone on smoking cessation. A randomized clinical trial. JAMA 2020; 324: 1844-1854.

Authors: Eisenberg MJ, Hébert-Losier A, Windle SB, Greenspoon T, Brandys T, Fülöp T et al.

Scientific Surgery

A randomized trial comparing antibiotics with appendectomy for appendicitis. N Engl J Med 2020; 383: 1907-1919.

Authors: The CODA Collaborative

Scientific Surgery

Role of compression after radiofrequency ablation of varicose veins: a randomised controlled trial. Eur J Vasc Endovasc Surg 2020; 60: 108-117.

Authors: Onwudike M, Abbas K, McElvenny DM

Scientific Surgery

Randomized controlled trial of vacuum therapy for intermittent claudication. J Vasc Surg 2020; 71: 1692-1701.

Authors: Hageman D, Fokkenrood HJP, van Deursen BAC, Gommans LNM, Cancrinus E, Scheltinga MRM et al.

Scientific Surgery

Preoperative patient-specific flow predictions to improve arteriovenous fistula maturation (Shunt Simulation Study): a randomised controlled trial. Eur J Vasc Endovasc Surg 2020; 60: 98-106.

Authors: Zonnebeld N, Tordoir JHM, van Loon MM, de Smet AA, Huisman LC, Cuypers PW et al.

Scientific Surgery

Long-term oncologic results after stenting as a bridge to surgery versus emergency surgery for malignant left-sided colonic obstruction. A multicenter randomized controlled trial (ESCO Trial). Ann Surg 2020; 272: 703-708.

Authors: Arezzo A, Forcignanò E, Bonino MA, Balagué C, Targarona E, Borghi F et al.

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