Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis. N Engl J Med 2017; 377: 2240-2252.

Authors: Vedantham S, Goldhaber SZ, Julian JA, Kahn SR, Jaff MR, Cohen DJ et al.

Scientific Surgery

Handcrafted vacuum-assisted device for skin ulcers treatment versus traditional therapy, randomized controlled trial. World J Surg 2017; 41: 386–393.

Authors: Gonzalez IG, Angel MAL, Baez MVJ, Flores BR, Ferretiz MDM, Woolf SV et al.

Scientific Surgery

Rivaroxaban or aspirin for extended treatment of venous thromboembolism. N Engl J Med 2017; 376: 1211-1222.

Authors: Weitz JI, Lensing AWA, Prins MH, Bauersachs R, Bayer-Westendorf J, Bounameaux H et al.

Scientific Surgery

Randomised controlled trial: potential benefit of a footplate neuromuscular electrical stimulation device in patients with chronic venous disease. Eur J Vasc Endovasc Surg 2017; 53: 114-121.

Authors: Ravikumar R, Williams KJ, Babbaer A, Lane TRA, Moore HM, Davies AH et al.

Scientific Surgery

Post-operative benefit of compression therapy after endovenous laser ablation for uncomplicated varicose veins: a randomised trial. Eur J Vasc Endovasc Surg 2016; 52: 847-853.

Authors: Wang KYR, Qin J, Yang X, Yin M, Liu X, Jiang M et al.

Scientific Surgery

Timing of chemical thromboprophylaxis and deep vein thrombosis in major colorectal surgery: a randomized clinical trial. Ann Surg 2016; 264: 632-639.

Authors: Zaghiyan KN, Sax HC, Miraflor E, Crossman D, Wagner W, Mirocha J et al.

Scientific Surgery

Systematic review and meta-analysis of utility of graduated compression stockings in prevention of post-thrombotic syndrome. Eur J Vasc Endovasc Surg 2016; 51: 838-845.

Authors: Skervin AL, Thapar A, Franchini AJ, Prandoni P, Shaloub J, Davies AH et al.

Scientific Surgery

One versus two years of elastic compression stockings for prevention of post-thrombotic syndrome (OCTAVIA study): randomised controlled trial. BMJ 2016; 353: i2691.

Authors: Mol GC, van de Ree MA, Klok FA, Tegelberg MJ, Sanders FB, Koppen S et al.

Scientific Surgery

Same site recurrence is more frequent after endovenous laser ablation compared to high ligation and stripping of the great saphenous vein: 5-year results of a randomised clinical trial (RELACS). Eur J Vasc Endovasc Surg 2015; 50: 648-656.

Authors: Rass K, Frings N, Glowacki P, Graber S, Tilgen W, Vogt T et al.

Scientific Surgery

Five-year follow-up of a randomized, controlled trial comparing saphenofemoral ligation and stripping of the great saphenous vein with endovenous laser ablation (980 nm) using local tumescent anesthesia. J Vasc Surg 2016; 63: 420-428.

Authors: Gauw SA, Lawson JA, van Vlijmen-van Keulen CJ, Pronk P, Gaastra MTW, Mooij MC et al.

Scientific Surgery

Tinzaparin vs warfarin for treatment of acute venous thromboembolism in patients with active cancer. A randomized clinical trial. JAMA 2015; 314: 677-686.

Authors: Lee AYY, Kamphuisen PW, Meyer G, Bauersachs R, Janas MS, Jarner MF et al for the CATCH Investigators et al.

Scientific Surgery

Ambulatory Varicosity avUlsion Later or Synchronized (AVULS): a randomized clinical trial. Ann Surg 2015; 261: 654-661.

Authors: Lane TRA, Kelleher D, Shepherd AC, Franklin IJ, Davies AH

Scientific Surgery

Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism. A randomized clinical trial. JAMA 2015; 313:

Authors: Mismetti P, Laporte S, Pellerin O, Ennezat P-V, Couturaud F, Elias A et al for the PREPIC2 Study Group et al.

Scientific Surgery

Efficacy and safety of the new oral anticoagulants dabigatran, rivaroxaban, apixaban, and edoxaban in the treatment and secondary prevention of venous thromboembolism: a systematic review and meta-analysis of phase III trials. Eur J Vasc Endovasc Surg. 2014; 48: 565-575.

Authors: Kakkos SK, Kirkilesis GI, Tsolakis IA

Scientific Surgery

Randomized trial comparing cyanoacrylate embolization and radiofrequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg 2015; 61: 985–994.

Authors: Morrison N, Gibson K, McEnroe S, Goldman M, King T, Weiss R et al. et al.

Scientific Surgery

A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. J Vasc Surg 2015; 61: 741–746.

Authors: Nandhra S, El-Sheikha J, Carradice D, Wallace T, Souroullas P, Samuel N et al. et al.

Scientific Surgery

Therapeutic effect of compression stockings versus no compression on isolated superficial vein thrombosis of the legs: a randomized clinical trial. Eur J Vasc Endovasc Surg 2014; 48: 465-471.

Authors: Boehler K, Kittler H, Stolkovich S, Tzaneva S

Scientific Surgery

Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding and intracranial haemorrhage. A meta-analysis. JAMA 2014; 311: 2414-2421.

Authors: Chatterjee S, Chakraborty A, Weinberg I, Kadakia M, Wilensky RL, Sardar P et al. et al.

Scientific Surgery

Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 2014; 370: 1402-1411.

Authors: Meyer G, Vicaut E, Danays T, Agnelli G, Becattini C, Beyer-Westendorf J et al. et al.

Scientific Surgery

Compression therapy versus surgery in the treatment of patients with varicose veins: a RCT. Eur J Vasc Endovasc Surg 2014; 47: 670-677.

Authors: Sell H, Vikatmaa P, Alback A, Lepantalo M, Malmivaara A, Mahmoud O et al. et al.

Scientific Surgery

A randomised trial comparing treatments for varicose veins. N Engl J Med 2014; 371: 1218-1227.

Authors: Brittenden J, Cotton SC, Elders A, Ramsay CR, Norrie J, Burr J et al. et al.

Scientific Surgery

Preoperative enoxaparin versus postoperative semuloparin thromboprophylaxis in major abdominal surgery: a randomized controlled trial. Ann Surg 2014; 259: 1073-1079.

Authors: Kakkar AK, Agnelli G, Fisher W, George D, Lassen MR, Mismetti P et al. et al.

Scientific Surgery

Clinical and cost-effectiveness of compression hosiery versus compression bandages in treatment of venous leg ulcers (Venous leg Ulcer Study IV, VenUS IV): a randomised controlled trial. Lancet 2014; 383:871-879.

Authors: Ashby RL, Gabe R, Ali S, Adderley U, Bland JM, Cullum NA et al. et al.

Scientific Surgery

Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial. Lancet 2014; 383: 880-888.

Authors: Kahn SR, Shapiro S, Wells PS, Rodger MA, Kovacs MJ, Anderson DR et al. et al.

Scientific Surgery

Thromboelastogram-guided enoxaparin dosing does not confer protection from deep venous thrombosis: a randomized controlled pilot trial. J Trauma Acute Care Surg 2014; 76:

Authors: Louis SG, Van PY, Riha GM, Barton JS, Kunio NR, Underwood SJ et al. et al.

Scientific Surgery

A randomized study on 1-week versus 4-week prophylaxis for venous thromboembolism after laparoscopic surgery for colorectal cancer. Ann Surg 2014; 259: 665-669.

Authors: Vedovati MC, Becattini C, Rondelli F, Boncompagni M, Camporese G, Balzarotti R et al. et al.

Scientific Surgery

A multicentre randomized controlled trial evaluating balneotherapy in patients with chronic venous insufficiency. J Vasc Surg 59: 447-454.

Authors: Carpentier PH, Blaise S, Satger B, Genty C, Rolland C, Roques C et al. et al.

Scientific Surgery

Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins. 5-year outcomes from a randomised controlled trial. Vasc Endovasc Surg 2013; 47: 346–352.

Authors: Samuel N, Wallace T, Carradice D, Mazari FAK, Chetter IC

Scientific Surgery

Randomized controlled trial of ultrasound-assisted, catheter-directed thrombolysis for acute intermediate risk pulmonary embolism. Circulation 2014; 129: 479-486.

Authors: Kucher N, Boekstegers P, Muller OJ, Kupatt C, Beyer-Westendorf J, Heitzer T et al. et al.

Scientific Surgery

Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med 2013; 369: 799-808.

Authors: Agnelli G, Buller HR, Cohen A, Curto M, Gallus AS, Johnson M et al. et al.

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