Scientific Surgery Online Journals

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Scientific Surgery

Acute effects of graduated elastic compression stockings in patients with symptomatic varicose veins: a randomized double blind placebo controlled trial. Eur J Vasc Endovasc Surg 2018; 55: 118-125.

Authors: Kakkos SK, Timpilis M, Patrinos P, Nikolakopoulos KM, Papageorgopoulou CP, Kouri AK et al.

Scientific Surgery

Outcomes after angiography with sodium bicarbonate and acetylcysteine. N Engl J Med 2018; 378: 603-614.

Authors: Weisbord SD, Gallagher M, Jneid H, Garcia S, Cass A, Thwin S-S et al.

Scientific Surgery

Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial. Lancet 2018; 391: 219-229.

Authors: Anand S, Bosch J, Eikelboom JW, Connolly SJ, Diaz R, Widimsky P et al.

Scientific Surgery

Randomized clinical trial of negative pressure wound therapy for high-risk groin wounds in lower extremity revascularization . J Vasc Surg 2017; 66: 1814-1819.

Authors: Lee K, Murphy PB, Ingves MV, Duncan A, DeRose G, Dubois L et al.

Scientific Surgery

Effect of granulocyte-macrophage colony-stimulating factor with or without supervised exercise on walking performance in patients with peripheral artery disease. The PROPEL randomized clinical trial. JAMA 2017; 318: 2089-2098.

Authors: McDermott MM, Ferrucci L, Tian L, Guralnik JM, Lloyd-Jones D, Kibbe MR et al.

Scientific Surgery

Hyperbaric oxygen therapy in the treatment of ischemic lower- extremity ulcers in patients with diabetes: Results of the DAMO2CLES multicenter randomized clinical trial. Diabetes Care 2018; 41: 112-119.

Authors: Santema KT, Stoekenbroek RM, Koelemay MJ, Reekers JA, van Dortmont LM, Oomen A et al.

Scientific Surgery

Efficacy and safety of aspirin in patients with peripheral vascular disease: an updated systematic review and meta-analysis of randomized controlled trials. PLoS ONE 2017; 12: e0175283.

Authors: Mahmoud AN, Elgendy AY, Rambarat C, Mahtta D, Elgendy IY, Bavry AA et al.

Scientific Surgery

Low dose aspirin as adjuvant treatment for venous leg ulceration. BMJ 2017: 359: j5157.

Authors: Jull A, Wadham A, Bullen C, Parag V, Kerse N, Waters J et al.

Scientific Surgery

Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis. N Engl J Med 2017; 377: 2240-2252.

Authors: Vedantham S, Goldhaber SZ, Julian JA, Kahn SR, Jaff MR, Cohen DJ et al.

Scientific Surgery

Population screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial. Lancet 2017; 390: 2256–2265.

Authors: Lindholt JS, Sogaard R

Scientific Surgery

Comparative clinical effectiveness and cost effectiveness of endovascular strategy v open repair for ruptured abdominal aortic aneurysm. BMJ 2017; 359: j4859.

Authors: Improve Trial Investigators

Scientific Surgery

Endovascular repair of abdominal aortic aneurysm in patients physically ineligible for open repair: very long-term follow-up in the EVAR-2 randomized controlled trial. Ann Surg 2017; 266: 713-719.

Authors: Sweeting MJ, Patel R, Powell J, Greenhalgh RM, for the, EVAR Trial Investigators et al.

Scientific Surgery

Low-dose paclitaxel–coated versus uncoated percutaneous transluminal balloon angioplasty for femoropopliteal peripheral artery disease. Circulation. 2017; 135: 2227-2236.

Authors: Schroeder H, Werner M, Meyer D-R, Reimer P, Krüger K, Jaff MR et al.

Scientific Surgery

Randomized comparison of paclitaxel-eluting balloon and stenting versus plain balloon plus stenting versus directional atherectomy for femoral artery disease (ISAR-STATH). Circulation. 2017; 135: 2218-2226.

Authors: Ott I, Cassese S, Groha P, Steppich B, Hadamitzky M, Ibrahim T et al.

Scientific Surgery

Evaluation of cell therapy on exercise performance and limb perfusion in peripheral artery disease. Circulation. 2017; 135: 1417-1428.

Authors: Perin EC, Murphy MP, March KL, Bolli R, Loughran J, Yang PC et al.

Scientific Surgery

Rivaroxaban with or without aspirin in stable cardiovascular disease. N Engl J Med 2017; 377: 1319-1330.

Authors: Eikelboom JW, Connolly SJ, Bosch J, Dagenais GR, Hart RG, Shestakovska O et al.

Scientific Surgery

Paclitaxel-coated balloon reduces target lesion revascularization compared with standard balloon angioplasty. J Vasc Surg 2017; 65: 558–570.

Authors: Candy N, Ng E, Velu R

Scientific Surgery

A network meta-analysis of randomized controlled trials comparing treatment modalities for de novo superficial femoral artery occlusive lesions. J Vasc Surg 2017; 65: 234–245.

Authors: Antonopoulos CN, Mylonas SN, Moulakakis KG, Sergentanis TN, Sfyroeras GS, Lazaris AM et al.

Scientific Surgery

Primary stenting of the superficial femoral artery in intermittent claudication improves health related quality of life, ABI and walking distance: 12 month results of a controlled randomised multicenter trial. Eur J Vasc Endovasc Surg 2017; 53: 686-694.

Authors: Lindgren H, Qvarfordt P, Akesson M, Bergman S, Gottsater A, Jansson I et al.

Scientific Surgery

Efficacy and safety of alprostadil in patients with peripheral arterial occlusive disease Fontaine stage IV: results of a placebo-controlled randomized multicenter trial (ESPECIAL). Eur J Vasc Endovasc Surg 2017; 53: 559-566.

Authors: Lawall H, Pokrovsky A, Checinski P, Ratushnyuk A, Hamm G, Randerath O et al.

Scientific Surgery

Safety and efficacy of remote ischemic preconditioning in patients with severe carotid artery stenosis before carotid artery stenting. A proof-of-concept, randomized controlled trial. Circulation 2017; 135: 1325-1335.

Authors: Zhao W, Meng R, Ma C, Hou B, Jiao L, Zhu F et al.

Scientific Surgery

Low-dose aspirin for primary prevention of cardiovascular events in patients with type 2 diabetes mellitus. 10-year follow-up of a randomized controlled trial. Circulation. 2017; 135: 659-670.

Authors: Saito Y, Okada S, Ogawa H, Soejima H, Sakuma M, Nakayama M et al.

Scientific Surgery

Ticagrelor compared with clopidogrel in patients with prior lower extremity revascularization for peripheral artery disease. Circulation. 2017; 135: 241-250.

Authors: Schuyler Jones W, Baumgartner I, Hiatt WR, Heizer G, Conte MS, White CJ et al.

Scientific Surgery

Handcrafted vacuum-assisted device for skin ulcers treatment versus traditional therapy, randomized controlled trial. World J Surg 2017; 41: 386–393.

Authors: Gonzalez IG, Angel MAL, Baez MVJ, Flores BR, Ferretiz MDM, Woolf SV et al.

Scientific Surgery

Evacetrapib and cardiovascular outcomes in high-risk vascular disease. N Engl J Med 2017; 376: 1933-1942.

Authors: Lincoff AM, Nicholls SJ, Riesmeyer JS, Barter PJ, Brewer HB, Fox KAA et al.

Scientific Surgery

An evaluation of the effect of an angiotensin-converting enzyme inhibitor on the growth rate of small abdominal aortic aneurysms: a randomized placebo-controlled trial (AARDVARK). Eur Heart J 2016; 37: 3213-3221.

Authors: Bicknell CD, Kiru G, Falaschetti E, Powell JT, Poulter NR, for the et al.

Scientific Surgery

Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet 2017; 389: 1312–1322.

Authors: Nijssen EC, Rennenberg RJ , Nelemans PJ, Essers BA, Janssen MM, Vermeeren MA et al.

Scientific Surgery

Rivaroxaban or aspirin for extended treatment of venous thromboembolism. N Engl J Med 2017; 376: 1211-1222.

Authors: Weitz JI, Lensing AWA, Prins MH, Bauersachs R, Bayer-Westendorf J, Bounameaux H et al.

Scientific Surgery

Randomised controlled trial: potential benefit of a footplate neuromuscular electrical stimulation device in patients with chronic venous disease. Eur J Vasc Endovasc Surg 2017; 53: 114-121.

Authors: Ravikumar R, Williams KJ, Babbaer A, Lane TRA, Moore HM, Davies AH et al.

Scientific Surgery

Post-operative benefit of compression therapy after endovenous laser ablation for uncomplicated varicose veins: a randomised trial. Eur J Vasc Endovasc Surg 2016; 52: 847-853.

Authors: Wang KYR, Qin J, Yang X, Yin M, Liu X, Jiang M et al.

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